Juventudes y clases popular-intermediarias en la primavera chilena de 2019: sujetos y acción colectiva disruptiva en la disputa por la dignidad

Esta investigación aborda la protesta, los sujetos y sus características, así como las formas de acción colectiva disruptivas en el levantamiento popular de octubre de 2019 en Santiago de Chile. El objetivo es analizar y reflexionar, a partir de la constatación de la ausencia de un sujeto de la convocatoria de las protestas, el uso de las prácticas disruptivas en estas, tratando de problematizar su supuesta "espontaneidad". La metodología se basa en una perspectiva cualitativa y entrevistas en profundidad a intelectuales y actores de la protesta. A modo de conclusión, la protesta, lejos de ser "espontánea", debe interpretarse como resultado de los repertorios de acción conocidos e innovaciones, así como de redes informales de cooperación, en que la acción colectiva disruptiva fue dominante.

This research addresses the protest, the subjects and their characteristics, as well as the forms of disruptive collective action in the popular uprising of October 2019 in Santiago de Chile. The objective is to analyze and reflect about the absence of a predetermined subject calling for the protests, the use of disruptive practices in them, and discussing their presumed "spontaneity". The methodology is based on a qualitative perspective and indepth interviews with academics and participants in the protest. My argument is that the protest, far from being "spontaneous", should be interpreted as the result of known repertoires of action and innovations, as well as informal networks of cooperation in which disruptive collective action was dominant.

Research progress on the clinical effects of minimally disruptive medicine in patients with chronic diseases / 中华全科医师杂志

With the elevating prevalence and comorbidity rate of chronic diseases,the burden of disease treatment for patients is increasing and quality of life is declining. Recently, the minimal disruptive medicine(MDM)has attracted more attention and its positive impact has been recognized. In this article we review the research progress in the clinical effects of MDM on chronic disease patients,which would promote the exploration and implementation of scientific and effective treatment strategies for general practice in China.

A CASE STUDY ON COMPASSION FATIGUE AMONG TEACHERS HANDLING STUDENT WITH DISRUPTIVE BEHAVIOURS IN INCLUSIVE CLASSROOM

The case study highlights on examining the compassion fatigue among teachers handling student with disruptive behaviours in inclusive classroom. If a child has a diagnosis of disruptive behavior disorder, it may be decided to place him in a special classroom set up for more intensive behavior management. Compassion fatigue occurs when the person handling with the child with a disorder becomes so preoccupied with the disability of the child that it in turn makes the therapist or the helper stressful. Disruptive behavior disorders can seriously impact a child's daily life. Children with disruptive behavior disorders show ongoing patterns of uncooperative and defiant behaviors. Treatment procedures involve therapy for such children to reduce the behavioral issues and provide positive reinforcement to improve self-control. The present study adopted a qualitative approach, a semi-structured interview was conducted among six teachers to assess the compassion fatigue while handling student with disruptive behavior in three different inclusive schools. The teachers were interviewed individually on two occasions to gather information on the impact of this phenomenon. The interview data were coded and categorized using thematic analysis. Through this analysis, three criteria were generated, that is, preparation and adaptation of learning materials, instructional process, and interpersonal relationships. The results revealed that the six teachers go through different emotional problems due to disruptive behaviours exhibited by their students and had health-related issues. It also showed that teachers' were mostly concerned with the loss of their instructional time. As a result of this, these teachers were unable to deliver the curriculum within the allocated time. The teachers' reported that the impact is not only the disruptively behaved child but the learning of the rest of the students were also hindered due to the disruptive behavioural issues. The implications of the findings for teachers and further research are discussed

The prevalence of impulsive compulsive behaviors in patients treated with apomorphine infusion: a retrospective analysis / Prevalência de comportamentos impulsivo-compulsivos em pacientes tratados com infusão de apomorfina: análise retrospectiva

ABSTRACT Background: Impulsive compulsive behaviors (ICBs) can affect a significant number of Parkinson's disease (PD) patients. Objective: We have studied brain samples from a brain bank of PD patients who received apomorphine via continuous infusion in life to assess the prevalence and outcome of ICBs. Methods: A search on the Queen Square Brain Bank (QSBB) database for cases donated from 2005 to 2016 with a pathological diagnosis of idiopathic PD was conducted. Notes of all donors who used apomorphine via continuous infusion for at least three months were reviewed. Clinical and demographic data were collected, as well as detailed information on treatment, prevalence and outcomes of ICBs. Results: 193 PD cases, 124 males and 69 females, with an average age at disease onset of 60.2 years and average disease duration of 17.2 years were reviewed. Dementia occurred in nearly half of the sample, depression in one quarter, and dyskinesias in a little over 40%. The prevalence of ICBs was 14.5%. Twenty-four individuals used apomorphine infusion for more than three months. Patients on apomorphine had younger age at disease onset, longer disease duration, and higher prevalence of dyskinesias. The prevalence of de novo ICB cases among patients on apomorphine was 8.3%. Apomorphine infusion was used for an average of 63.1 months on an average maximum dose of 79.5 mg per day. Ten patients remained on apomorphine until death. Conclusions: Apomorphine can be used as an alternative treatment for patients with previous ICBs as it has low risk of triggering recurrence of ICBs.

RESUMO Antecedentes: Comportamentos impulsivo-compulsivos (CICs) podem acometer uma parcela significativa de indivíduos com doença de Parkinson (DP). Objetivo: Nós estudamos amostras de tecido cerebral de uma população de pacientes com DP de um banco de cérebros que receberam apomorfina por infusão contínua em vida, com a finalidade de avaliar a prevalência e o desfecho dos CICs. Métodos: Uma pesquisa no banco de dados do Banco de Cérebros de Queen Square foi conduzida à procura de doações recebidas entre 2005 e 2016 com diagnóstico anatomopatológico de DP idiopática. Os prontuários de todos os doadores que usaram apomorfina por infusão contínua por um período mínimo de três meses foram revisados. Dados clínicos e demográficos foram coletados, assim como informações detalhadas sobre o tratamento, prevalência e desfecho dos CICs. Resultados: 193 casos de DP, 124 do sexo masculino e 69 do sexo feminino, com idade média de início da doença de 60,2 anos e tempo médio de duração da doença de 17,2 anos, foram revisados. Aproximadamente metade dos casos apresentaram demência, um quarto depressão, e um pouco mais de 40% discinesias. A prevalência de CICs foi 14,5%. Vinte e quatro indivíduos usaram infusão de apomorfina por mais de três meses. Os pacientes que usaram apomorfina apresentaram DP mais cedo, maior duração da doença, e uma maior prevalência de discinesias. A prevalência de novos casos de CICs entre pacientes usando apomorfina foi de 8,3%. Infusão de apomorfina foi usada em média por 63,1 meses a um dose máxima média de 79,5 mg por dia. Dez pacientes permaneceram usando apomorfina até o óbito. Conclusões: Apomorfina pode ser usada como opção de tratamento alternativo para pacientes que apresentarem CICs no passado considerando seu baixo risco de causar recorrência de CICs.

Water column use by reef fishes of different color patterns

Color in animals responds to selective pressures and mediates the relationship between organism and environment. Reef fishes have the amplest variety of pigment cell types. This color patterns' variety may function as camouflage and be related to spatial use. We tested the hypothesis that the coloration of reef fish relates to water column stratum occupation. We predicted that sedentary animals connected to the background take advantage of background matching or disruptive patterns; more mobile demersal species apply disruptive coloration or motion-dazzle; and that pelagic species tend to have silvery bodies. We classified color patterns and categorized the water column stratum use for the Brazilian reef fishes in FishBase. Our analyses confirmed that irregular contrasting contour breaks, suggestive of disruptive coloration, occurs in benthic species and that silvering color was more prevalent in the pelagic stratum. Our raw data suggested a higher frequency of contrasting regular stripes, typical of motion-dazzle, in demersal species. However, the considerable uncertainty around estimates did not confirm this pattern. Reef fishes coloration is correlated to occupation of different strata in the water column. This can be interpreted as fishes being adapted to these habitats and partially explaining the richness of color patterns among them.(AU)

A cor nos animais responde a pressões seletivas e media a relação entre organismo e ambiente. Peixes recifais têm a maior variedade de tipos de células de pigmento. Essa variedade de padrões de coloração pode funcionar como camuflagem e estar relacionada ao uso espacial. Nós testamos a hipótese de que a coloração dos peixes recifais está relacionada à ocupação do estrato da coluna d'água. Previmos que animais sedentários conectados ao fundo aproveitam a semelhança ao fundo ou padrões disruptivos; espécies demersais mais móveis aplicam coloração disruptiva ou deslumbramento de movimento; e que espécies pelágicas tendem a apresentar corpos prateados. Classificamos os padrões de coloração e categorizamos o uso do estrato da coluna d'água para os peixes recifais brasileiros no FishBase. Nossas análises confirmaram que quebras de contorno irregulares, sugerindo coloração disruptiva, ocorrem em espécies bentônicas e que a cor prateada prevaleceu no estrato pelágico. Nossos dados brutos sugeriram uma maior frequência de listras contrastantes, típicas do deslumbramento de movimento, em espécies demersais. Mas a considerável incerteza dessas estimativas não confirmou esse padrão. A coloração dos peixes recifais está correlacionada com a ocupação de diferentes estratos da coluna d'água. Isso pode ser interpretado como peixes sendo adaptados a estes habitats, explicando em parte a riqueza de padrões de coloração entre eles.(AU)

Assessment of therapeutic strategies for management of impulse control disorder in Parkinson's disease / Evaluación de las estrategias terapéuticas en trastornos del control de impulsos en enfermedad de Parkinson

ABSTRACT Background: Impulse control disorders (ICD) occur frequently in individuals with Parkinson's disease. So far, prevention is the best treatment. Several strategies for its treatment have been suggested, but their frequency of use and benefit have scarcely been explored. Objective: To investigate which strategy is the most commonly used in a real-life setting and its rate of response. Methods: A longitudinal study was conducted. At the baseline evaluation, data on current treatment and ICD status according to QUIP-RS were collected. The treatment strategies were categorized as "no-change", dopamine agonist (DA) dose lowering, DA removal, DA switch or add-on therapy. At the six-month follow-up visit, the same tools were applied. Results: A total of 132 individuals (58.3% men) were included; 18.2% had at least one ICD at baseline. The therapeutic strategy most used in the ICD group was no-change (37.5%), followed by DA removal (16.7%), DA switch (12.5%) and DA lowering (8.3%). Unexpectedly, in 20.8% of the ICD subjects the DA dose was increased. Overall, nearly 80% of the subjects showed remission of their ICD at follow-up. Conclusions: Regardless of the therapy used, most of the subjects presented remission of their ICD at follow-up Further research with a longer follow-up in a larger sample, with assessment of decision-making processes, is required in order to better understand the efficacy of strategies for ICD treatment.

Resumen Antecedentes: Los trastornos del control de impulsos (TCI) son frecuentes en personas con enfermedad de Parkinson. A la fecha, la prevención es el mejor tratamiento. Existen varias estrategias sugeridas para su tratamiento, pero su frecuencia de uso y beneficio ha sido escasamente explorada. Objetivo: Investigar qué estrategia es la más utilizada en un entorno de la vida real y su tasa de respuesta. Métodos: Se realizó un estudio longitudinal. En la evaluación inicial, se recopiló el tratamiento actual y el estado del TCI de acuerdo con el QUIP-RS. La estrategia de tratamiento se clasificó como "sin cambios", reducción de la dosis de agonista de la dopamina (AD), eliminación de AD, cambio de AD o terapia complementaria. En la visita de seguimiento a los 6 meses, se aplicaron las mismas herramientas. Resultados: Se incluyeron un total de 132 (58.3% hombres) personas. El 18.2% tenía al menos un TCI al inicio del estudio. La estrategia terapéutica más utilizada en el grupo de TCI fue sin cambios (37.5%), seguida de eliminación de DA (16.7%), cambio de AD (12.5%) y reducción de DA (8.3%). En el 20.8% de los sujetos con TCI se aumentó la dosis de AD. Casi el 80% de los sujetos tuvieron una remisión del TCI al seguimiento. Conclusiones: Independientemente de la terapia utilizada, la mayoría de los sujetos tuvieron una remisión del TCI. Se requiere más investigación con un seguimiento y una muestra mayor para evaluar l proceso de toma de decisiones para comprender mejor la eficacia de las estrategias.

Rasgos de personalidad, bienestar y malestar psicológico en usuarios de redes sociales que presentan conductas disruptivas online / Personality traits, well-being and psychological distress in users who present online disruptive behavior

Resumen El presente estudio se propuso investigar perfiles de usuarios de redes sociales que presentan conductas disruptivas online. Para tal fin se diseñó un índice que permite evaluar el nivel en el que se presentan dichas conductas y se analizó la relación entre la intensidad de la conducta disruptiva online con variables sociodemográficas, motivos de usos de redes, variables de personalidad (normales, patológicas y rasgos vinculados a tríada oscura), bienestar y malestar psicológico. Participaron 858 adultos (421 hombres y 437 mujeres) que tenían en promedio 39.16 años (DE = 14.14). Para la recolección de datos se administraron: Dark Triad Scale, Big Five Inventory, Inventario para Trastornos de la Personalidad para el DSM-5, Mental Health Continuum . Depression, Anxiety and Stress Scale, y se diseñaron dos escalas: Índice de Conductas Disruptivas Online y Motivos de Utilización de Redes Sociales. En cuanto a las variables sociodemográficas, se halló que los más jóvenes de sexo masculino y que no trabajaban eran quienes presentaban un mayor nivel de comportamientos disruptivos online. En cuanto a los motivos de uso de redes, se observó que preferían usarlas con fines meramente exhibicionistas, de ocio o para iniciar nuevas relaciones. Por otro lado, en relación con rasgos de personalidad, aquellos que diferenciaban los perfiles en cuanto a la intensidad de las conductas disruptivas fueron: bajos niveles de responsabilidad y altos niveles de desinhibición, narcisismo y maquiavelismo. Por último, se demostró que presentar este tipo de conductas se asocia con mayor nivel de estrés y menor de bienestar social.

Abstract The present study focused on the analysis of online disruptive behavior that usually occurs among social network users. Individuals who perpetrate such behavior are commonly known as trolls or haters (Cheng, Danescu-Niculescu-Mitzil, & Leskovec, 2015). In general, they post comments, photos or provocative videos that do not pursue any purpose other than annoying or obtaining pleasure or fun (Brandel, 2007; Phillips, 2011). Recent studies have shown that certain personality traits are associated with the presence of such disruptive behavior. In this research, we studied normal personality traits, psychopathological traits, and dark personality traits in relation to disruptive behavior. The normal personality traits were considered from the classic Five Factor Model (FFM) - Openness to experience, Conscientiousness, Extraversion, Agreeableness, Neuroticism (Costa, & McCrae, 1985); the psychopathological traits, from the latest version of the DSM - Negative Effect, Detachment, Antagonism, Disinhibition and Psychoticism (DSM-5, American Psychiatric Association, 2013); and the dark personality traits from the so-called Dark Triad model - Narcissism, Machiavellianism and Psychopathy (Palthus, & Williams, 2002). This latter model has a growing interest in the international literature, related to dysfunctional Internet use, particularly to social networks. Therefore, the present study aimed to analyze profiles of social network users who present online disruptive behavior. For this purpose, an index was designed to assess the level of occurrence of such behaviors. First, the relationship between the intensity of online disruptive behavior and sociodemographic variables (i. e., sex, age, studies, occupation and nationality) and motives for social network use (i. e., Relationship maintenance; Passing time and Exhibitionism; Relationship Initiation and Search for companionship) were assessed. Then, the relationships among personality variables (i. e., normal, psychopathological and traits related to the dark triad); well-being (i. e., emotional, social and personal) and psychological distress (i. e., anxiety, stress and depression) were analyzed. The sample consisted of 858 adults (421 men, 49.1 % and 437 women, 50.9 %) with a mean age of 39.16 years (SD = 14.14). The majority (67.9 %; n = 583) lived in Buenos Aires, Argentina). For data collection, the following questionnaires were used: Dark Triad Scale (DTS), Big Five Inventory (BFI), Personality Disorder Inventory (PID-5-BF), the Mental Health Continuum (MHC-SF), and the Depression, Anxiety and Stress Scale (DASS-21). Additionally, two scales were designed: Online Disruptive Behavior Index, and Motives for Social Networks Use. The SPPS 24.0 statistical package was used for data analysis. Overall, the results are consistent with those reported in the international literature. Regarding sociodemographic variables, it was found that male, younger and unemployed individuals are those who presented higher level of online disruptive behavior. Considering motives for social network use, it was observed that individuals who tend to behave in a dysfunctional manner, preferred to use social networks purely for exhibitionism, pastime or relationships initiation. Regarding personality traits, those who differentiated profiles in terms of intensity of disruptive behaviors were: low levels of responsibility and high levels of disinhibition, narcissism and Machiavellianism. Thus, it might be concluded that the overall personality profile tends to be dysfunctional in terms of its characteristics. Finally, it was shown that presenting this type of behavior is associated with higher levels of stress and lower levels of social wellbeing. Therefore, it might be interpreted that although individuals who behave disruptively tend to obtain gratification from injury and deceit to others, this behavior does not result in positive results for them, but rather results in feelings of discomfort from a personal and social point of view.

Pulsão de destruição ­ o disruptivo em ação ­ entre o tanático e o criativo: repercussões na pandemia e no racismo do dia a dia de nossas vidas / Destruction drive ­ the disruptive in action ­ between the tanatic and the creative: repercussions in day by day of pandemic and racismo of our lives / Pulsión de destrucción - lo disruptivo en acción - entre lo tanático y lo creativo: repercusiones en la pandemia y en el racismo diarios de nuestras vidas

O presente trabalho parte da ideia de caracterizar o disruptivo no pensamento freudiano. Como ponto de partida, toma o trabalho de 1914, À guisa de introdução ao narcisismo, por reconhecer nele um momento primeiro de ruptura na teoria pulsional vigente: libido do Eu versus libido objetal. Durante o trajeto, sinaliza marcas desse processo e direciona-se para o disruptivo que se instala em termos metapsicológicos, com maior consistência, com o advento da pulsão de morte. A pulsão de destruição, como agente do disruptivo em sua relação com Eros, desenhará caminhos que permitem vislumbrar destinos tanáticos ou criativos. Com essa concepção metapsicológica como indicador, busca-se refletir a respeito da interação entre o disruptivo da pandemia viral e o disruptivo da virulência do racismo e seus desdobramentos criativos na efetivação, pelo coletivo da humanidade, de posturas antirracistas. Tal contexto alberga uma interrogação pontual: como a pandemia, em seu efeito disruptivo, está relacionada com a percepção em toda a sua sensorialidade, em grande escala, de norte a sul, daquilo que mantinha-se parcialmente silencioso e invisível, o racismo? (AU)

The present article begins from the idea of characterize the disruptive in the freudian's thoughts. Is takes as a starter point the work of 1914, On narcissism: an introduction, for recognize it as a first moment of rupture in the current drive theory: self libido versus object libido. In this path, it signals marks of this process and orientate to the disruptive that develops in metapsychological terms, with great consistency, with the advent of the death drive. The destruction drive, as a disruptive agent, in its relation with Eros, will draw paths that allow glimpse its tanatic fate or criative fate. From this metapsychological conception, as an indicator, seeks to reflect the interaction between the disruptive in the viral pandemic and the disruptive in the racism virulence, and its criatives developments in the effectuation of anti-racist postures, by the humanity collective. Context that holds an punctual interrogation: how the pandemic, with its disruptive effect, is related with the perception in all its sensoriality, in big scale, from north to south, with what was, in part, silence and inivisible: the racism? (AU)

El objetivo inicial del presente trabajo es caracterizar lo disruptivo en el pensamiento freudiano. Se toma como punto de partida el célebre texto de 1914 Introducción del narcisismo por reconocer en él un primer momento de ruptura en la teoría pulsional vigente hasta ese momento, que distinguía la libido del Yo y la libido de objeto. En ese recorrido, se irán señalando marcas de dicho proceso orientándose hacia lo disruptivo, que se instalará con mayor consistencia, en términos metapsicológicos, con el advenimiento de la pulsión de muerte. La pulsión de destrucción, como agente de lo disruptivo, en su relación con Eros, trazará caminos que permiten vislumbrar sus destinos tanáticos o creativos. Tomando esa concepción metapsicológica como indicador, busco reflejar la interacción entre lo disruptivo de la pandemia viral y lo disruptivo de la virulencia del racismo, así como sus desdoblamientos creativos en la adopción de posturas antirracistas por parte del colectivo humano. En este contexto se plantea una interrogación puntual: ¿cómo la pandemia, con su efecto disruptivo, está relacionada con la percepción en toda su sensorialidad, en gran escala, de norte a sur, de aquello que, en parte, se mantenía silencioso e invisible, el racismo?

Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or anticarcinogens that present a general killing mechanism through the physical disruption of cell membranes, in contrast to conventional chemotherapeutic drugs, which act on precise targets such as DNA or specific enzymes. Owing to their rapid action, broad-spectrum activity, and mechanisms of action that potentially hinder the development of resistance, MDPs have been increasingly considered as future therapeutics in the drug-resistant era. Recently, growing experimental evidence has demonstrated that MDPs can also be utilized as adjuvants to enhance the therapeutic effects of other agents. In this review, we evaluate the literature around the broad-spectrum antimicrobial properties and anticancer activity of MDPs, and summarize the current development and mechanisms of MDPs alone or in combination with other agents. Notably, this review highlights recent advances in the design of various MDP-based drug delivery systems that can improve the therapeutic effect of MDPs, minimize side effects, and promote the co-delivery of multiple chemotherapeutics, for more efficient antimicrobial and anticancer therapy.

Ajuste personal y conductas disruptivas en alumnado de primaria / Personal Adjustment and Disruptive Behaviors in Primary School Students

Resumen. Objetivo. Estudiar las relaciones entre variables de ajuste personal y las conductas disruptivas en un grupo de 136 alumnos y alumnas de primaria de entre 9 y 12 años. Método. Estudio de campo observacional, de metodología no experimental y transversal. Se utilizaron varios cuestionarios para medir la autoestima, la personalidad, el estrés y las competencias emocionales de los y las estudiantes, así como un cuestionario ad hoc elaborado para el registro de las conductas disruptivas. Resultados. Los resultados indican relaciones significativas positivas entre conductas disruptivas y estrés escolar, así como negativas con autoestima, estabilidad, competencia y comprensión emocional. Las diferencias son significativas según el género, manifestándose las conductas inadecuadas en menor medida en el caso de las niñas.

Abstract. Objective. This study analyses the relationships between personal adjustment and disruptive behaviors in a group of 136 primary school students between the ages of 9 and 12. Method. This field observation study used a non-experimental, cross-sectional methodology. Several questionnaires were used to measure students' self-esteem, personality, stress, and emotional competencies. Moreover, an ad hoc questionnaire was created to record disruptive behaviors. Results. The results indicate significant positive relationships between disruptive behaviors and school stress, as well as negative ones with self-esteem, stability, competence, and emotional understanding. The differences are significant according to gender, with inappropriate behaviors manifesting to a lesser extent in the case of girls.

Conductas disruptivas en adolescentes en situación de deprivación sociocultural / Disruptive behaviors in adolescents in a situation of sociocultural deprivation

RESUMEN Introducción: La deprivación sociocultural es un fenómeno multifactorial que incide en los procesos de desarrollo y adaptación de los individuos a sus contextos de socialización y aprendizaje. De ahí la importancia del estudio de los factores predisponentes de la deprivación sociocultural y la disrupción escolar, entre tanto brinda insumos interpretativos que favorecen la comprensión de la influencia de las dinámicas socioambientales en los procesos relacionales y de convivencia en la escuela. Objetivo: Caracterizar las conductas disruptivas en adolescentes en situación de deprivación sociocultural favoreciendo un marco de comprensión que permita entender la génesis de los factores de disruptividad en las dinámicas interaccionales Escuela-Comunidad. Método: A nivel metodológico se suscribió en el paradigma cualitativo con enfoque histórico-hermenéutico y método micro-etnográfico, se utilizaron técnicas como las entrevistas a profundidad y observación participante; el estudio contó con 80 estudiantes provenientes de las comunas 10, 6 y 3, 30 de género femenino y 50 de género masculino con rango de edad de los 13 a 17 años en la ciudad de Pasto, Nariño, con reportes de disrupción escolar y cuyos ambientes sociocomunitarios evidencian factores predisponentes a la deprivación sociocultural. Resultados: Se logran identificar las conductas disruptivas que afectan el proceso de enseñanza aprendizaje y los factores de deprivación sociocultural asociados, seguidamente expone las conductas disruptivas con incidencia en los procesos de convivencia escolar, y se bosqueja un marco interpretativo sobre las consecuencias de la disruptividad en las dinámicas escolares. Conclusiones: La deprivación sociocultural evidencia una situación de desventaja social al momento que los escolares expuestos a sus factores predisponentes cuentan con menos herramientas para la adaptación y aprovechamiento de la experiencia escolar, es además, uno de los detonantes de la disrupción escolar, fenómeno multifactorial que afecta tanto los procesos convivenciales como académicos; y un factor predictor del fracaso escolar.

ABSTRACT Introduction: Sociocultural deprivation is a multifactorial phenomenon that affects the processes of development and adaptation of individuals to their contexts of socialization and learning. Hence, the importance of studying the predisposing factors of sociocultural deprivation and school disruption, meanwhile, it provides interpretative inputs that promote the understanding of the influence of socioenvironmental dynamics on the relationship and coexistence processes in the school. Objective: To characterize the disruptive behaviors in adolescents in a situation of sociocultural deprivation, favoring a framework of understanding that allows us to understand the genesis of disruptive factors in the interaction dynamics of the School-Community. Method: At the methodological level, the qualitative paradigm was subscribed with a historical-hermeneutical approach and a micro-ethnographic method, using techniques such as in-depth interviews and participant observation; The study included 80 students from communes 10, 6, and 3, 30 female and 50 male, with an age range of 13 to 17 years in the Pasto city, with reports of school disruption and whose socio-community environments show predisposing factors to the sociocultural deprivation. Results: It is possible to identify the disruptive behaviors that affect the teaching-learning process and the associated sociocultural deprivation factors, then it exposes the disruptive behaviors with incidence in the processes of school coexistence, and outlines an interpretative framework on the consequences of the disruption in school dynamics. Conclusions: Sociocultural deprivation shows a situation of social disadvantage at the time that schoolchildren exposed to its predisposing factors have fewer tools for adapting and taking advantage of school experience, it is also one of the triggers of school disruption, a multifactorial phenomenon that affects both coexistence and academic processes; and a predictor of school failure.

O impacto do COVID-19 em famílias e o excesso como objeto pulsional / The COVID-19 impact on families and the excess as drive object

Este ensaio reflete sobre o impacto da pandemia associada ao COVID-19 em microssistemas familiares. Articula-se a incidência da pandemia enquanto evento no processamento psíquico dos indivíduos com o fenômeno de busca de um estado mental impulsionado pelo excesso, como objeto pulsional. Postula-se que a situação atual criada pelo COVID-19 constituiu um entorno disruptivo, mas não necessariamente traumático. Segundo tais considerações, sugerem-se estratégias que podem mitigar o impacto da pandemia nas relações interpessoais no contexto familiar e clínico.

This essay reflects the impact of the pandemic associated with COVID-19 on family microsystems. It articulates the incidence of the pandemic as an event in the psychic processing of individuals with the phenomenon of seeking mental states driven by excess, as a drive object. It is postulated that the current situation created by the COVID-19 constituted a disruptive environment, but not necessarily traumatic. According to these considerations, this essay suggests some strategies which could mitigate the impact of the pandemic on interpersonal relationships within the family context and in clinical settings.

Evaluación de síntomas no motores y descontrol de impulsos en usuarios con enfermedad de Parkinson por el médico en atención primaria

Background: Nonmotor symptoms of Parkinson disease significantly hamper the quality of life of patients and have prognostic significance. Aim: To evaluate the presence of nonmotor symptoms in patients with Parkinson disease. Material and Methods: A structured interview was carried out in 32 patients aged 74 ± 9 years (53% men) with Parkinson disease asking specifically for impulse control disorders and dopaminergic dysregulation. The following scales were also applied: Hoehn & Yahr scale, Montreal Cognitive Assessment, Geriatric depression scale, Nonmotor symptom scale and REM sleep scale. Results: A high frequency of nonmotor symptoms was recorded, specially mood, sleep, urinary and gastrointestinal problems and impulse control disorders. Conclusions: Nonmotor symptoms must be actively sought and managed in patients with Parkinson disease.

Parent-teacher report reliability on the fourth edition of the Swanson, Nolan and Pelham scale in a Brazilian clinical sample of children and adolescents with attention-deficit/hyperactivity disorder

Abstract Background Parents and teachers can be valuable sources of information for characterizing children's ADHD-related impairments in different environments. However, evidence indicated that those categories of informants often provide conflicting responses in formal assessment scales, which may challenge diagnostic decisions regarding the condition. Objective: We aimed to investigate reliability rates between parents and teachers of children and adolescents with and without ADHD using SNAP IV. Methods 199 children and adolescents aged 6 to 17 years were evaluated for ADHD symptoms using parent-rated and teacher-rated SNAP IV scales. Intraclass correlation coefficients were analyzed for ADHD domains (inattention and hyperactivity/impulsivity), as well as for defiant-oppositional behavior. Results Reports from parents and teachers showed low reliability for all ADHD domains. Parents' scores on the SNAP IV were higher than those of teachers. Parents and teachers provided highly discrepant responses concerning to the presence and severity of ADHD in children and adolescents, which might result from intrinsic aspects related to their daily functioning in different settings. Discussion Clinicians should consider those trends in parental and teachers' responses when interpreting results from informant-based instruments for detecting ADHD.

Technological Advances and Medicine: A Narrative Review in the light of COVID-19

@#The current global pandemic, known as COVID-19, poses challenges to healthcare systems worldwide. At the same time, it has provoked a collective focus on new and disruptive technology and stimulated the application of such technologies to disease control and containment efforts. Some of the innovations that have played the most significant roles have come from the fields of artificial intelligence, big data analytics, and communications technology. The current situation provides a good opportunity to relook how medical people engage with technological advances. This narrative review attempts to provide a historical context to the adoption of technology and of technical developments in Singapore and discusses the impact of disruptive technology in healthcare.

Las tecnologías disruptivas y su aplicación en la medicina con vistas al 2030 / Disruptive technologies and their application in medicine: a vision to 2030

Introducción: La aplicación de las tecnologías disruptivas en el contexto de la salud pública permite mejorar la calidad de sus servicios y la calidad de vida de las personas. Objetivo: Analizar el desarrollo de las tecnologías disruptivas que han incidido hasta hoy en la práctica médica y cómo este desarrollo se prevé que transformará la forma en que se ejerce la medicina en la actualidad y hacia el 2030. Métodos: Investigación documental con enfoque cualitativo, basada en la búsqueda y selección de información para conocer el estado del arte sobre el tema. Se realizaron análisis de casos y ejemplos exitosos en el uso de las tecnologías que aparecen en la literatura. Para la búsqueda se utilizaron los vocablos tecnologías disruptivas, salud pública, medicina preventiva, participativa, predictiva y personalizada. Se aplicaron entrevistas y grupos focales para delimitar los temas fundamentales y para identificar barreras y buenas prácticas. Conclusiones: Las tecnologías disruptivas deben ser empleadas en todas las áreas del conocimiento humano, con énfasis en la medicina, permitiendo evaluar de forma permanente sus beneficios y sus riesgos. Estas tecnologías están directamente relacionadas con el alcance de la medicina de las 4P y su aplicación en los sistemas de salud, y para que su gestión sea efectiva será necesario romper barreras que faciliten su proceso(AU)

Introduction: The application of disruptive technologies in the context of public health allows you to improve the quality of their services and people's life quality. Objective: To analyse the development of disruptive technologies that have influenced until nowadays the medical practice and how this development it is anticipated that will transform the way that medicine is practiced today and toward 2030. Methods: Documentary research with qualitative approach, based on the search and selection of information to know the state of the art on the subject. Analysis of cases and examples of successful experiences in the use of the technologies that appear in the literature were made. For the search were used the words disruptive technologies, public health, preventive medicine, participatory, predictive and personalized. Interviews and focus groups were applied to identify the key issues and to identify barriers and good practices. Conclusions: Disruptive technologies should be used in all areas of human knowledge, with an emphasis on medicine, allowing to assess on a permanent basis their benefits and risks. These technologies are directly related to the scope of the medicine of the 4P and its application in health systems, and for its management to be effective it will be necessary to break down barriers to facilitate their process(AU)

Implementing a community-based parent training behavioral intervention for autism spectrum disorder / Capacitação parental para manejo de comportamentos disruptivos para tea em intervenção comportamental / Tea: capacitación de padres para manejo de conductas problemáticas

The autism spectrum disorder (ASD) affects developmental areas early in life and on families exert significant burden both emotionally and economically. This paper is a non-controlled, multicenter study to train caregivers of ASD individuals displaying disruptive behavior and deficit of communication, based on Applied Behavior Analysis. Results showed a reduction in the disruptive behavior measured by the Aberrant Behavior Checklist (ABC) and also the caregivers' depression and anxiety symptoms assessed by the Hamilton Scale. Group interventions may be an alternative for reaching a higher share of the population.

O transtorno do espectro do autismo (TEA) afeta precocemente áreas de desenvolvimento e resulta em uma sobrecarga significativa para as famílias, tanto emocional quanto economicamente. Este é um estudo não controlado, multicêntrico, com o objetivo de capacitar, com base na Análise Aplicada do Comportamento, cuidadores de indivíduos com TEA que apresentam comportamento disruptivo e deficit de comunicação. Os resultados mostraram redução nos comportamentos disruptivos, medidos pelo Aberrant Behavior Checklist (ABC), e também nos sintomas de depressão e ansiedade dos cuidadores, avaliados pela Escala de Hamilton. As intervenções em grupo podem ser uma alternativa viável para atingir uma parcela maior da população.

O transtorno do espectro do autismo (TEA) afeta precocemente áreas de desenvolvimento e resulta em uma sobrecarga significativa para as famílias, tanto emocional quanto economicamente. Este é um estudo não controlado, multicêntrico, com o objetivo de capacitar, com base na Análise Aplicada do Comportamento, cuidadores de indivíduos com TEA que apresentam comportamento disruptivo e deficit de comunicação. Os resultados mostraram redução nos comportamentos disruptivos, medidos pelo Aberrant Behavior Checklist (ABC), e também nos sintomas de depressão e ansiedade dos cuidadores, avaliados pela Escala de Hamilton. As intervenções em grupo podem ser uma alternativa viável para atingir uma parcela maior da população.

Trastorno de control de impulsos (TCI) en enfermedad de Parkinson / Impulse control disorders (ICD) in Parkinson's disease

RESUMEN Los trastornos del control de impulsos (TCI) son complicaciones psiquiátricas de la enfermedad de Parkinson (EP), cada vez más reconocidos, pero que persisten subdiagnosticados y pueden llegar a ser muy disruptivos para la vida familiar del paciente, en especial si no son detectados a tiempo. Si bien uno de sus principales riesgos es el uso de agonistas dopaminérgicos, estos no son su única causa, se pueden ver sin relación con medicamentos o con cualquier tratamiento para la EP. Por lo tanto, se debe interrogar sistemáticamente por su presencia y educar al paciente y su familia para que sean reportados en cualquier momento. El objetivo de este capítulo es describir los diferentes tipos de TCI, sus factores de riesgo y tratamiento.

SUMMARY Impulse Control Disorders (ICD) are psychiatric complications of Parkinson's Disease (PD), increasingly recognized, but which persist underdiagnosed and can be vert disruptive to the patient's family life, especially if they are not detected in time. Although one of its main risks is the use of dopamine agonists, these are not the only cause, they can be seen without realtion to medications ot any treatment for PD, therefore it should be questioned systematically by their presence and educate the patient and his family to be reported at any time. The objective of this chapter is to describe the different types of ICD, their risk factors and treatment.

Irritabilidad como síntoma transdiagnóstico / Irritability as a transdiagnostic Symptom

Resumen. La irritabilidad es un síntoma transdiagnóstico que atraviesa la barrera de las patologías internalizantes y externalizantes. Se define como un umbral bajo para experimentar la ira en respuesta a la frustración y es uno de los síntomas más comunes en niños y adolescentes. Las conductas relacionadas con la ira apropiadas para el desarrollo tienden a reflejar frustración en contextos esperados, mientras que la irritabilidad crónica es inapropiada para la situación. La presentación de la irritabilidad, crónica o episódica, es crucial para comprender su significado psicopatológico, en particular porque las estructuras de la irritabilidad episódica y crónica son separables y permanecen estables a lo largo del tiempo. Existen varios estudios acerca de la irritabilidad en patologías como trastorno afectivo bipolar y trastorno de desregulación disruptiva del estado del ánimo, en ambos casos es importante plantearse como punto de partida la identificación de la episodicidad. La irritabilidad también se encuentra presente en el trastorno de personalidad límite observándose dentro de una inestabilidad afectiva debida a una reactividad notable del estado de ánimo. Estas emociones tienen un correlato anatómico relacionado con deficiencias de los circuitos frontolímbicos. Para el manejo de la irritabilidad en las distintas patologías, la evidencia del tratamiento incluye terapia cognitivo conductual, intervención de los padres, mindfulness, pero existe una necesidad apremiante de investigación sobre el tratamiento farmacológico complementario.

Irritability is a transdiagnostic symptom that crosses the barrier between internalizing and externalizing pathologies. It is defined as a low threshold to experience anger in response to frustration and it is one of the most common symptoms in children and adolescents. Behaviors related to appropriate developmental anger tend to reflect frustration in expected contexts, while chronic irritability is inappropriate to the situation. The presentation of irritability, chronic or episodic, is crucial to understanding its psychopathological meaning, particularly because the structures of episodic and chronic irritability are separable and remain stable over time. There are several studies about irritability in pathologies such as bipolar affective disorder and disruptive mood dysregulation disorder, in both cases it is important to consider the identification of episodicity as a starting point. Irritability is also present in borderline personality disorder, where it is expressed as an affective instability due to a remarkable reactivity of the state of mind. These emotions have been anatomically related to deficiencies of the frontolimbic circuits. For the management of irritability in different patholo-gies, the evidence includes cognitive behavioral therapy, parental intervention, mindfulness, but there still is a pressing need for research on complementary pharmacological treatment.

A Comparative Study on the Effectiveness of Individual and Group Play Therapy on Symptoms of Oppositional Defiant Disorder among Children / 가정의학회지

BACKGROUND: This research compared the effectiveness of play therapy provided individually or in groups for oppositional defiant disorder (ODD) symptoms among children. METHODS: This was a randomized controlled trial that used a multi-stage random sampling method. Participants included 45 children aged 6 to 10 years old with ODD, all of whom had been referred to medical consultation centers in Ahvaz, Iran in 2012. Experimental groups consisted of 15 children receiving individual play therapy and 15 receiving group play therapy, while the control group consisted of 15 randomly selected children. Data were collected using the child behavior checklist parent report form and teacher report form, along with clinical interviews with the parents. Play therapy took place weekly for eight total sessions; individual sessions lasted 45 minutes each, while group sessions were each 60 minutes in duration. Participants were assessed in three stages, including pre-intervention, post-intervention, and at 2-month follow-up. PASW SPSS ver. 18.0 software (SPSS Inc., Chicago, IL, USA) and analysis of covariance analysis methods were used to analyze data. RESULTS: Results showed meaningful decreases in ODD symptoms in the experimental groups in comparison with the control group, based on parent reporting (P≤0.001 and F=129.40) and the teacher reports additionally showed meaningful decreases in ODD symptoms in the experimental groups compared to the control group, (P≤0.001 and F=93.14). Furthermore, the effects were maintained after 2 months. CONCLUSION: This research supports the efficacy of individual and group play therapy for the treatment of ODD in children, as well as the consistency of the effects at 2-month follow-up.